24 companies, including Microsoft, Google, NVIDIA, OpenAI, AWS, and AMD, join the U.S. government's 'Genesis Mission' to promote the use of AI for scientific discovery

The U.S. Department of Energy (DOE) announced that it has signed agreements with 24 interested parties to advance Mission Genesis , a national initiative to harness the power of AI to accelerate scientific discovery, strengthen national security, and advance energy innovation.
Energy Department Announces Collaboration Agreements with 24 Organizations to Advance the Genesis Mission | Department of Energy
https://www.energy.gov/articles/energy-department-announces-collaboration-agreements-24-organizations-advance-genesis
The Genesis Mission, launched on November 24, 2025 under the direction of President Donald Trump, aims to build an integrated AI platform that leverages federal scientific datasets, trains scientifically based models, and creates AI agents to test new hypotheses, automate research workflows, and accelerate scientific breakthroughs.
On December 18, 2025, a meeting was held with DOE Administrator Chris Wright and other relevant officials from various agencies, and new agreements were signed with the following 24 organizations:
Accenture
AMD
・Anthropic
Armada
・Amazon Web Services (AWS)
・Cerebras
・CoreWeave
Dell
・DrivenData
Google
・Groq
Hewlett Packard Enterprise
・IBM
Intel
Microsoft
・NVIDIA
・OpenAI
・Oracle
・Periodic Labs
Palantir
・Project Prometheus
・Radical AI
・xAI
・XPRIZE
'This effort advances the American AI Action Plan, which calls for removing barriers to innovation, reducing reliance on foreign adversaries, and unleashing the full power of America's scientific enterprise. This will drive the creation of a scalable national infrastructure that will push the boundaries of science at unprecedented speed and ensure the benefits of AI reach every corner of the nation,' said Michael Kratsios, Assistant to the President and Director of the Office of Science and Technology Policy. 'The 24 partnerships announced today are just the first step in fulfilling President Trump's directive to bring together companies, universities, nonprofits, and federal agencies on the Genesis mission.'
'This unprecedented effort will bring together America's best scientists and federal research datasets to accelerate scientific progress,' Secretary Wright said. Other companies that have expressed their support have also issued statements.
Thanks to President Trump, Genesis Mission stands as THE flagship science initiative of our generation.
— Secretary Chris Wright (@SecretaryWright) December 18, 2025
This unprecedented effort will bring together America's brilliant scientists and federal research datasets to accelerate scientific breakthroughs. pic.twitter.com/n4MlRP8Aqi
NVIDIA commented, 'We are working with the DOE to integrate the computing and AI tools researchers need, connecting government, industry, and academia. NVIDIA has already worked with the DOE to advance weather forecasting, computational fluid dynamics, and structural mechanics using its AI science model, NVIDIA Apollo.
NVIDIA's John Josephakis, Global VP for HPC, AI, and Supercomputing, participated in a Genesis Mission industry roundtable today with @SecretaryWright , @mkratsios47 , and @dariogila .
— NVIDIA Newsroom (@nvidianewsroom) December 18, 2025
NVIDIA will work with @ENERGY to bring together the computing and AI tools researchers need,… pic.twitter.com/KevCkdpWo7
AWS has supported the Genesis mission from the beginning with cloud infrastructure and other technologies.
AWS: Powering America's Genesis Mission from day one | AWS Public Sector Blog
https://aws.amazon.com/jp/blogs/publicsector/aws-powering-americas-genesis-mission-from-day-one/
Anthropic provides AI agents that address DOE's top priorities, a model context protocol server that connects its AI model, Claude, with scientific instruments and tools, and Claude's expertise in relevant scientific workflows.
Working with the US Department of Energy to unlock the next era of scientific discovery \ Anthropic
https://www.anthropic.com/news/genesis-mission-partnership
OpenAI is focused on advancing basic and applied research and strengthening American leadership in AI and advanced computing.
Deepening our collaboration with the US Department of Energy | OpenAI
https://openai.com/index/us-department-of-energy-collaboration/
Other companies that have issued statements expressing their support for the Genesis Mission include Dell , Intel , Google , Palantir , Radical AI , CoreWeave , and AMD .
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