Vaccine developed that does not require injection and does not require refrigeration
In order to immunize in advance of infections such as influenza, measles, mumps, etc., 'vaccines' send viruses and bacteria that have weakened or inactivated pathogenicity into the body. The vaccine is usually given using a syringe, but Maria Croyle, a professor of pharmacy at the University of Texas at Austin, reports that he has successfully developed a 'non-injection vaccine.'
Novel technology for storage and distribution of live vaccines and other biological medicines at ambient temperature | Science Advances
Vaccines without needles – new shelf-stable film could revolutionize how medicines are distributed worldwide
https://theconversation.com/vaccines-without-needles-new-shelf-stable-film-could-revolutionize-how-medicines-are-distributed-worldwide-132479
There are various types of vaccines, and representative ones are 'live vaccines', 'inactivated vaccines' and 'toxoids'. Live vaccines are vaccinated by weakening the pathogenicity of pathogenic viruses and bacteria, inactivated vaccines are vaccinated with pathogenic viruses and bacteria, and toxoids are toxic using toxins produced by bacteria. It is lost and then inoculated.
In any case, since the vaccine uses raw materials of biological origin, it is greatly affected by ultraviolet rays and temperature and loses its efficacy over time. Therefore, the storage and management of vaccines requires equipment that can be stored in a refrigerator. However, preparing and maintaining such equipment comes at a certain cost and is almost impossible to prepare in some areas.
In addition, vaccination is basically done by injection. It has been pointed out that injection needles can be a route of infection for infectious diseases such as hepatitis and AIDS if not properly managed.
The vaccine that Professor Croyle has been developing since 2007 can be inoculated orally by sandwiching the vaccine with a thin film containing natural ingredients such as sugar and salt. Since the cost is low and the manufacturing process is relatively simple, it will be possible to provide the vaccine at an affordable price. And because it's flat and space-saving, Professor Croyle argues that it will be possible to store and distribute large numbers of vaccines.
The biggest breakthrough in this research project, according to Professor Croyle, was that the virus in the vaccine, despite being left unattended for three years, when the virus was sandwiched between films as part of the Ebola virus vaccine development. It was said that it was found that more than 95% was active and did not lose its effectiveness as a vaccine.
Professor Croyle said, 'In a campaign to vaccinate 18 million children a month in the Philippines in 2004, 19.5 million syringes were discarded', and filmless needleless vaccine spread That would solve the problem of medical waste as well as vaccine storage.
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