"Rejuvenating medicine" succeeds in animal clinical, application of "scolding unexpected results" that scientists say to human being will be carefully advanced

ByMulan

By administering to old-age mice, the Dutch scientists succeeded in developing drugs that realize a dramatic rejuvenating effect, such as restoring liver function, enhancing stamina, making body hair shorter, and research results are published in scientific journalsCellIt was announced in. Attention is drawn to whether this medicine can rejuvenate human beings.

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging: Cell
http://www.cell.com/cell/fulltext/S0092-8674(17)30246-5

Drug 'reverses' aging in animal tests - BBC News
http://www.bbc.com/news/health-39354628

A research team at the Erasmus University Medical Center in the Netherlands developed medicines to reduce senescent cells and conducted animal experiments using mice. Cells that have undergone cell division (senescent cells) accumulate with age and are suspected to be involved in further aging by releasing inflammation-causing chemical substances, but the research team at Erasmus University aged We have developed a drug that has the effect of selectively killing cells and washing them out of the body. And, when drugs were administered to mice, we confirmed that they had stopped aging and had a rejuvenating effect.

In experiments, drugs were administered using older rats equivalent to 90 years old at the age of human beings. An elderly mouse given drugs three times a week recovered liver function and the distance traveled by exercise wheels placed in the cage doubled as compared to before drug administration. In addition, there have also appeared changes in appearance that researchers did not anticipate, "body hair becomes fluffy", and have succeeded in dramatic rejuvenation.


According to the research team, it is clear that animal experiments with mice have no effect on symptoms accompanying aging such as osteoporosis, but it has been confirmed that special side effects have not been confirmed at the present time as the experiment was continued for one year Thing. Dr. Peter De Keyser, a research team, believes that medicines developed do not affect normal tissues at all, as jokingly as "mice do not talk".

Dr. Dasco Irick, who studies stem cells at King's College in London, still has doubts as to the effect of the drug developed by the Erasmus research team, so it is necessary to continue careful experiments and verification in the future "It is impossible to overlook (dramatic achievement)," while saying that it is desirable to reserve knowledge until further high-quality research is done.